pentobarbital will reduce the level or outcome of diazepam buccal by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch. Sturdy or moderate CYP3A4 inducers may maximize amount of diazepam elimination; therefore, efficacy of diazepam may be lessened.
pentobarbital will minimize the level or result of abemaciclib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Stay clear of or Use Alternate Drug. Coadministration of abemaciclib with sturdy CYP3A4 inducers minimizes plasma focus of abemaciclib and its metabolites.
Keep an eye on Intently (1)pentobarbital will reduce the extent or outcome of levamlodipine by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will lessen the level or impact of pantoprazole by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Significance Unknown.
Administer barbiturates with caution in patients with hepatic hurt and at reduced doses originally; barbiturates really should not be administered to individuals exhibiting the premonitory indications of hepatic coma
Contraindicated (1)pentobarbital will reduce the level or influence of dienogest/estradiol valerate by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Women shouldn't select estradiol valerate/dienogest as their contraceptive whilst working with robust CYP3A4 inducers because of possible reduce in contraceptive efficacy.
With therapeutic doses of TCAs, barbiturates boost metabolism and decrease blood concentrations of TCAs.
pentobarbital will lessen the extent or outcome of eplerenone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Importance Unknown.
pentobarbital will lessen the extent or outcome of budesonide by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.
pentobarbital decreases effects of hemin by pharmacodynamic antagonism. Use Caution/Check. Drugs that enhance delta-aminolevulinic acid synthetase may minimize hemin impact.
pentobarbital will lower the extent or result of tamoxifen by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.
pentobarbital will lessen the level or outcome more info of atorvastatin by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.
pentobarbital will lessen the level or influence of darifenacin by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.
pentobarbital will lessen the extent or result of glecaprevir/pibrentasvir by affecting hepatic/intestinal enzyme CYP3A4 metabolism.